High Concentration EPA/DHA Combination. EPA and DHA, the two main components of omega-3 from fish oil, are essential for growth and development throughout the human life cycle.
Nordic Naturals Ultimate Omega contains 70% pure omega-3, and is purified through molecular distillation to ensure the absence of impurities including PCBs and heavy metals.
Suggested Use: Two soft gels daily, with food, or as directed by your health care professional or pharmacist.
General Nutrient Support
Ultimate Omega offers a high concentration of both EPA and DHA. This formulation was used in a bipolar disorder study at Harvard University.
* High concentration of EPA and DHA
* 640 mg omega-3s per soft gel
* Meets European Pharmacopoeia Standards
* Molecularly distilled for purity—no PCBs, heavy metals, or pesticides
* Rosemary extract added for extended freshness
* Great-tasting lemon flavor
Ingredients: purified deep sea fish oil (from anchovies and sardines), soft gel capsule (gelatin, water, glycerin, natural lemon oil), natural lemon oil, d-alpha tocopherol, rosemary extract
Two 1000 mg Soft Gels Contain:
EPA: 650 mg
DHA: 450 mg
Other Omega-3s: 180 mg
Vitamin E: 30 IU
Research
2005-12-15
Study to evaluate impact of pure fish oil among Pro football players
Yates A, Bradley JP, Maroon J, et al. Evaluation of lipid profiles, inflammatory markers and the use of Omega-3 EFA in Professional Football Players. Initiation: 2006
Introduction: The risk of cardiovascular disease becomes significant in males at age 30. Because many professional football players carry a large amount of weight and are required to exert extreme bursts of maximal physical effort, they make up a unique class of individuals that may have a higher risk for adverse cardiac events such as heart attacks and death.
Family heart history, obesity and other diet and lifestyle factor also play a major role. Cardiac risk assessment is critical to ensure the health of these premier athletes.
The Pittsburgh Steelers have undertaken a rigorous health screening program using both conventional physical exams and now state of the art blood test to assess these risks.
This same physical contact often results in painful joints which are often treated with NSAIDs. The recent withdrawal of Vioxx and the concern of serious side effects make long term use of the COX-2 family of NSAIDs a significant risk factor.
For this evaluation we plan to evaluate the use of Omega-3 EFAs for both their cardiovascular protective effect, by reducing vascular inflammation and plaque stabilization and their ability to relieve joint tissue inflammation and the associated pain.
Materials and Methods: The study will recruit a total of 40 players of which 20 will be given 2,800 mg of omega-3 EFA (EPA/DHA) at the start of the pre-season for the duration of the season. The other 20 players will be the control group. Both groups will be asked to complete questionnaires, diary logs, NSAIDs usage and pain assessments. Routine pre-, mid- and post season cardiac risk assessment blood work and history and physical exams data will also be collected and results used for this analysis.
With this pilot analysis of 40 NFL players we hope to assess any potential beneficial affects of omega-3 EFA on both reducing cardiac risk by improved blood inflammation and lipid markers and by quantifying any reduction in NSAIDs use and improved pain scores in the treatment group.
The Beneficial Effect of Omega-3 Liquid and Ultimate Omega Liquid on Glucose Uptake and Cell Livability in L6 Muscle Cell Line
F. Deyhim, O. Olivarez. Diabetes, 2006;55(1):A382
Texas A&M University, Kingsville, TX.
Previous research has shown that populations eating a lot of fish containing omega-3 fatty acids have lower rates of type 2 diabetes compared with those eating less fish.
The objective of the present study was to evaluate whether saponified fish oil influences glucose uptake and survival rate of L6 muscle cells. The L6 rat muscle cells were grown to confluence in either low (5 mM) or high (25 mM) glucose media for seven days in the presence of either 3 μg/ml or 30 μg/ml saponified Omega-3 Liquid (863 mg omega-3), Ultimate Omega Liquid (1601 mg omega-3g), DHA (580 mg omega-3), and Complete Omega-3.6.9
Liquid (706 mg omega-3 + 83 mg GLA) for the final 24 hours of incubation.
After 24 hours of incubation with varied doses of saponified fish oil, cells were exposed to 2-deoxy-glucose, 14C glucose, or 3H-palmitate in the presence of insulin (1000 nm). Also, superoxide anion production and cell livability were assessed. 14C glucose incorporation to glycogen, glucose uptake and palmitate uptake per gram protein, and cell livability significantly decreased (P<0.05), while superoxide anion production significantly increased (P<0.05) after exposure to 25 mM glucose compared to 5 mM glucose media.
Despite a numerical dose response, saponified Omega-3 Liquid, Ultimate Omega Liquid, and DHA significantly increased (p<0.05) while Complete Omega-3.6.9 Liquid numerically improved glucose uptake. The fish oil examined in this study did not (P>0.1) affect 14C glucose incorporation to glycogen, palmitate uptake, or superoxide anion production. Saponified Omega-3 exhibited a numerical improvement in cell livability compared to Ultimate Omega and a significant (P<0.05) enhancement in cell livability compared to DHA and Complete Omega-3.6.9. Saponified Ultimate Omega exhibited a numerical improvement in cell livability compared to DHA and a significant (P<0.05) enhancement in cell livability compared to Complete Omega-3.6.9.
In conclusion, the potential benefit of fish oil on glucose uptake and cell livability depends on the concentration of omega-3 taken up by the L6 muscle cells.
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